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Isabelle Vilgrain Selected Research

cadherin 5

6/2022Inhibition of Vascular Endothelial Cadherin Cleavage Prevents Elastic Fiber Alterations and Atherosclerosis Induced by Intermittent Hypoxia in the Mouse Aorta.
10/2021VE-cadherin cleavage in sleep apnoea: new insights into intermittent hypoxia-related endothelial permeability.
12/2018A Biomimetic Lipid Membrane Device Reveals the Interaction of Cancer Biomarkers with Human Serum Lipidic Moieties.
1/2018The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma.
12/2017Soluble vascular endothelial (VE) cadherin and autoantibodies to VE-cadherin in rheumatoid arthritis patients treated with etanercept or adalimumab.
1/2017Soluble VE-cadherin in metastatic breast cancer: an independent prognostic factor for both progression-free survival and overall survival.
8/2014VE-cadherin Y685F knock-in mouse is sensitive to vascular permeability in recurrent angiogenic organs.
7/2014VE-cadherin, a potential marker for endothelial cell activation during hereditary angioedema attacks.
1/2013Evidence for post-translational processing of vascular endothelial (VE)-cadherin in brain tumors: towards a candidate biomarker.
1/2012Soluble VE-cadherin in rheumatoid arthritis patients correlates with disease activity: evidence for tumor necrosis factor α-induced VE-cadherin cleavage.
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Isabelle Vilgrain Research Topics

Disease

2Vascular Remodeling
06/2022 - 08/2014
2Hypoxia (Hypoxemia)
06/2022 - 10/2021
2Kidney Neoplasms (Kidney Cancer)
12/2018 - 01/2018
2Breast Neoplasms (Breast Cancer)
01/2018 - 01/2017
2Neoplasms (Cancer)
01/2018 - 01/2013
2Rheumatoid Arthritis
12/2017 - 01/2012
2Edema (Dropsy)
08/2014 - 07/2011
2Hereditary Angioedemas
07/2014 - 07/2011
2Atrophy
10/2003 - 01/2003
1Atherosclerosis
06/2022
1Uveitis
10/2020
1Ocular Toxoplasmosis
10/2020
1Renal Cell Carcinoma (Grawitz Tumor)
01/2018
1Urticaria (Hives)
01/2016
1Abdominal Pain (Pain, Abdominal)
01/2016
1Angioedema
07/2015
1Rare Diseases (Rare Disease)
07/2015
1Glioma (Gliomas)
01/2013
1Brain Neoplasms (Brain Tumor)
01/2013
1Inflammation (Inflammations)
01/2012
1Vascular System Injuries
01/2012
1Pathologic Neovascularization
02/2005
1Body Weight (Weight, Body)
10/2003

Drug/Important Bio-Agent (IBA)

11cadherin 5IBA
06/2022 - 07/2011
4Biomarkers (Surrogate Marker)IBA
12/2018 - 01/2013
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2021 - 01/2013
3BradykininIBA
01/2016 - 07/2011
2Phosphotransferases (Kinase)IBA
06/2022 - 10/2021
2Tyrosine (L-Tyrosine)FDA Link
10/2021 - 01/2013
2Biological ProductsIBA
10/2020 - 02/2005
2Adrenocorticotropic Hormone (ACTH)FDA Link
10/2003 - 01/2003
2Dexamethasone (Maxidex)FDA LinkGeneric
10/2003 - 01/2003
1Apolipoproteins E (ApoE)IBA
06/2022
1saracatinibIBA
06/2022
1pazopanibFDA Link
06/2022
1AcriflavineIBA
06/2022
1Reactive Oxygen Species (Oxygen Radicals)IBA
10/2021
1AntioxidantsIBA
10/2021
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2021
1Retinaldehyde (Retinal)IBA
10/2020
1AntibodiesIBA
10/2020
1Immunoglobulin G (IgG)IBA
10/2020
1Tyrosine Kinase InhibitorsIBA
01/2018
1Hormones (Hormone)IBA
01/2018
1Bevacizumab (Avastin)FDA Link
01/2018
1Sunitinib (Sutent)FDA Link
01/2018
1Etanercept (Enbrel)FDA Link
12/2017
1AutoantibodiesIBA
12/2017
1Adalimumab (Humira)FDA Link
12/2017
1Metalloproteases (Metalloproteinases)IBA
01/2013
1Matrix Metalloproteinases (MMPs)IBA
01/2013
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2012
1Kallikreins (Kallikrein)IBA
07/2011
1Angiopoietin-1IBA
10/2003
1Proteins (Proteins, Gene)FDA Link
10/2003
1CorticosteroneIBA
10/2003
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
10/2003
1Corticotropin Receptors (ACTH Receptor)IBA
10/2003
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2003

Therapy/Procedure

1Continuous Positive Airway Pressure
10/2021
1Biological Therapy
01/2018
1Therapeutics
01/2018